WebNov 24, 2013 · Phosphohexomutases catalyze the interconversion between hexose-6-phosphate and hexose-1-phosphate and play important roles in polysaccharide synthesis. In Synechocystis sp. PCC 6803, sll0726 is predicted to encode PGM (phosphoglucomutase), slr1334 is predicted to encode a PGM/PMM (phosphomannomutase) bifunction enzyme. WebAbstract. Enzymes in the α-d-phosphohexomutases superfamily catalyze the reversible …

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WebJul 28, 2013 · Protein expression and purification. D4 from PMM/PGM was expressed and purified with a yield of 160 mg/l, as described (Schramm et al. 2010), but with the use of 13 C glucose (Sigma-Isotec) supplemented by 5 % (v/v) 13 C, 15 N-labeled Celtone CN (Cambridge Isotope Laboratories). Its N-terminal hexahistidine tag added 20 residues to … WebAbstract. The enzyme phosphomannomutase/phosphoglucomutase (PMM/PGM) from the … shaney brown

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WebFeb 1, 2024 · Most enzymes in the α-D-phosphohexomutase superfamily catalyze the reversible conversion of 1- to 6-phosphosugars. They play important roles in carbohydrate and sugar nucleotide metabolism, and participate in the biosynthesis of polysaccharides, glycolipids, and other exoproducts. Mutations in genes encoding these enzymes are … WebJun 7, 2012 · PMM/PGM proteins comprise a widespread enzyme family involved in prokaryotic carbohydrate biosynthesis. They represent one sub-group of the α-D-phosphohexomutase enzyme superfamily, according to their similar preference for glucose and mannose-based phosphosugar substrates . The enzyme reaction entails an … WebThis protein, a phosphohexomutase, is part of a large family of enzymes that function in all organisms from bacteria to humans, and play important roles in cellular metabolism. We used this phosphohexomutase as a model system, to study important issues related to protein structure and enzyme function. shane yearian trophy whitetails