Web13 Apr 2024 · Lassa virus (LASV) is the causative agent for Lassa fever (LF) currently endemic in West Africa. There is no approved vaccines and antivirals against LASV infection. ... Intriguingly, the NP ExoN motif is highly conserved among arenavirus family, regardless of pathogenicity and viral capability to suppress host innate immune … Though first described in the 1950s, the virus causing Lassa disease was not identified until 1969. The virus is a single-stranded RNA virus belonging to the virus family Arenaviridae. About 80% of people who become infected with Lassa virus have no symptoms. 1 in 5 infections result in severe disease, … See more The incubation period of Lassa fever ranges from 6–21 days. The onset of the disease, when it is symptomatic, is usually gradual, starting with fever, general weakness, and malaise. After a few days, headache, sore … See more Because the symptoms of Lassa fever are so varied and non-specific, clinical diagnosis is often difficult, especially early in the course of the disease. Lassa fever is difficult to distinguish from other viral haemorrhagic fevers … See more Humans usually become infected with Lassa virus from exposure to urine or faeces of infected Mastomysrats. Lassa virus may also be spread between humans through direct contact with the blood, urine, faeces, … See more The antiviral drug ribavirin seems to be an effective treatment for Lassa fever if given early on in the course of clinical illness. There is no evidence … See more

Lassa fever — the road ahead Nature Reviews Microbiology

WebLassa fever is an animal-borne (zoonotic), acute viral illness, caused by the Lassa virus, a member of the arenavirus family of viruses. The animal reservoir, or host, of Lassa … Web16 Feb 2024 · Lassa fever is an acute viral haemorrhagic illness, belonging to the virus family Arenaviridae, that lasts between two and 21 days, according to the World Health … rusted things

Knowledge of Lassa fever, its prevention and control practices …

Web9 Feb 2024 · Lassa virus is a member of the arenavirus family. The disease was first described in the 1950s, and the virus was identified in 1969 after 2 missionary nurses died from the disease in the... Web16 Feb 2024 · What is Lassa fever? Scientists first identified the virus causing Lassa fever in 1969. It belongs to the Arenaviridae family. According to the UK Health agency, … Web17 Mar 2015 · In some areas of Sierra Leone and Guinea, more than half of the population has antibodies against Lassa virus (LASV; family Arenaviridae), the etiologic agent of LF (5,6). According to various estimates, 300,000–500,000 cases of LF result in 5,000–10,000 deaths annually in West Africa (6,7). rusted slicer dicer wasteland 3