WebNov 9, 2016 · First, the false positive rates (FPRs; FDR < 0.1) of the GSEA-GP methods for the four gene statistics (mod-t, SNR, Ranksum and FC) and their absolute counterparts … WebThen, gene set enrichment analysis (GSEA) was applied to further analyze pathway regulation, with an adjusted p-value <0.05 and a false discovery rate (FDR) <0.25. Ferroptosis-related genes were obtained from the FerrDb V2 database, and cuproptosis-related genes were obtained from the literature. We constructed a novel signature (CRF) …
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WebNov 9, 2024 · We identified 56 different enriched KEGG pathways between subtypes 1 and 2, 4 pathways between subtypes 1 and 3, and 44 between subtypes 2 and 3, respectively, by gene differential expression analysis and GSEA (FDR < 0.25, Tables S2–S4). These imaging subtype-associated KEGG pathways included cell cycle, ECM-receptor … WebApr 14, 2024 · For GSEA analysis normalised read counts for all conditions were used and genes were ranked using the signal-to-noise metric and FDR and NES were calculated using 1000 gene-set permutation. sports direct oban
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WebTo identify signaling pathways activated in liver cancer, we conducted the GSEA between low and high EIF2B5 expression data sets. GSEA reveals significant differences (FDR <0.25, NOM P-value<0.05) in the enrichment of MSigDB Collection (c2.cp.biocarta.v6.2.symbols.gmt and h.all.v6.2.symbols.gmt), and the details are shown … http://baderlab.org/CancerStemCellProject/VeroniqueVoisin/AdditionalResources/GSEA WebGene Set Enrichment Analysis (GSEA) is a powerful analytical method for interpreting gene expression data. It evaluates cumulative changes in the expression of groups of multiple genes defined based on prior biological knowledge. ... (FDR) q-values: consider a set significantly enriched if its NES has an FDR q-value below 0.25. For more ... sports direct not paying minimum wage