WebSep 13, 2024 · Here we show that it is possible to encapsulate proteins in a ferritin cage by exploiting electrostatic interactions with its negatively charged interior. Positively supercharged green fluorescent protein is efficiently taken up by Archaeoglobus fulgidus ferritin in a tunable fashion. WebThe isolated, post-encapsulation protein cage shows bands corresponding to both GFP and TmFtn (lane 2). Lane 1 and lane 3 represent marker and free TmFtn, respectively (d) DLS showing no...
Efficient Self-Assembly of Archaeoglobus fulgidus Ferritin around ...
WebNov 20, 2024 · Enzyme Encapsulation by a Ferritin Cage Angew Chem Int Ed Engl. 2024 Nov 20;56(47):14933-14936. doi: 10.1002/anie.202408530. Epub 2024 Oct 12. Authors ... Here we show that it is possible to encapsulate proteins in a ferritin cage by exploiting … WebNov 22, 2024 · More importantly, upon encapsulation, ferritin shell greatly improved the water solubility, thermal stability, photostability, and cellular uptake activity of these small … do red carpet leases have inspection fees
Tailor-made active enzyme aggregates in vivo for efficient
WebJun 10, 2024 · Ferritin is an iron-storage protein nanocage that is assembled from 24 subunits. The hollow cavity of ferritin enables its encapsulation of various therapeutic agents; therefore, ferritin has been intensively investigated for drug delivery. The use of antibody-ferritin conjugates provides an effective approach for targeted drug delivery. WebFerritin nanocage with intrinsically disordered proteins and affibody: A platform for tumor targeting with extended pharmacokinetics. Journal of Controlled Release 2024, 267, 172 … WebNov 22, 2024 · More importantly, upon encapsulation, ferritin shell greatly improved the water solubility, thermal stability, photostability, and cellular uptake activity of these small bioactive compounds. This review aims to highlight recent advances in applications of ferritin cage as a novel vehicle in the field of food science and nutrition. do red cars attract police